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KMID : 0351619780190010021
Kyungpook Medical Journal
1978 Volume.19 No. 1 p.21 ~ p.29
Effects of Acute Carbon Monoxide Poisoning on the Electroencephalogram of the Rabbit


Kim Mi-Han

Abstract
In order to observe the effects of the acute carbon monoxide poisoning on experimental animals, rabbits were exposed to the 0.2 %and 0.5% carbon monoxide gas mixtures with room air. The duration of the exposure in the 0.2% concentration was 100 minutes and that in the 0.5% concentration was 30 minutes.
The EEG was recorded with the fronto-occipital bipolar lead.
The stainless steel needle electrodes were implanted extradurally through skull bone.
The EEG of rabbits in the acute carbon monoxide poisoning showed a generalized diminished voltage in the amplitude and a slightly decsea&ed frequency in file rhythm of the main waves. During the recovery period the relatively high voltage sl~~~v wave activity were observed on several occasions. The above EEG abnormalities were similar to tl:~e previously reported EEG findings in the rabbits exposed to the positive(=Gz) and negative acceleratron(Gz), and the rapid decompression.
There are individual variations in the length of the recovery period from the acute carbon monoxide poisoning at the same concentration of the gas mixture.
The individual variation of the recovery period of the EEG seems to be originated by the tolerance of each animal to the carbon monoxide poisoning and also the tolerance to the gas poisoning will largely depend upon the degree of the resultant brain hypoxia.
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